Biochemistry Dr. Sagar Dholariya Assistant Professor MBBS, MD BIOCHEMISTRY

Publications (Research papers):-

1. Clinical efficacy and safety of dasiglucagon in severe hypoglycemia associated with patients of type 1 diabetes mellitus: a systematic review and meta-analysis. Expert Rev Clin Pharmacol. 2022 Oct 25:1-11. doi: 10.1080/17512433.2023.2138343. Epub ahead of print. PMID: 36266088.
2. COVID-19-related liver injury:   Focus   on   genetic   and   drug-induced   perspectives.   World   J   Virol.   2023   Jan25;12(1):53-67. doi: 10.5501/wjv.v12.i 1.53. PMID: 36743658; PMCID: PMC9896591
3. Role of the tumor microenvironment and the influence of epigenetics on the tumor microenvironment in oral carcinogenesis: Potential implications January 2022. Critical Reviews in Oncogenesis. DOI: 10.1615/CritRevOncog.2022047088
4. Integrating cutting-edge methods to oral cancer screening, analysis, and prognosis. Critical Reviews in Oncogenesis. DOI: 10.1615/CritRevOncog.2023047772
5. Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection. World J Methodol. 2022 Sep 20;12(5):438-447. doi: 10.5662/wjm.v12.i5.438. PMID: 36186744; PMCID: PMC9516548.
6. Potential of cytochrome P450, a family of xenobiotic metabolizing enzymes, in cancer therapy. Antioxid Redox Signal. 2022 Oct 14. doi: 10.1089/ars.2022.0116. Epub ahead of print. PMID: 36242099
7. CRISPR/Cas9: A Molecular Tool for Ovarian Cancer Management beyond Gene Editing. Critical ReviewsTM in Oncogenesis 2022: 27(4):1–22.
8. Preeclampsia and Oxidative Stress: A Review. Current Innovations in Medicine and Medical Science. 2022.  Vol. 5, 102–109. https://doi.org/10.9734/bpi/cimms/v5/ 16536D
9. Association of the Human Leptin Receptor Gene (rs1137101;Gln223Arg) Polymorphism and Circulating Leptin in Patients with Metabolic Syndrome in the Indian Population. Ind J Clin Biochem (2022). https://doi.org/10.1007/s12291-022-01065-5.
10. Global research trends of interleukin-6 in SARS-CoV-2 infection. Indian Journal of Biochemistry and Biophysics (IJBB). 2022. DOI: 10.56042/ijbb.v59i5.60924
11. Emerging Variants of SARS-CoV-2 Virus: A Quick Glance. Indian J Clin Biochem. 2021 Oct;36(4):451-458. DOI: 10.1007/s12291-021-00991-0. Epub 2021 28th June. PMID: 34219999; PMCID: PMC8237041.
12. Utility of P-SEP, sTREM-1 and suPAR as Novel Sepsis Biomarkers in SARS-CoV-2 Infection. Indian J Clin Biochem. 2021 Oct 6:1-8. DOI: 10.1007/s12291-021-01008-6. Epub ahead of print. PMID: 34642555; PMCID: PMC8494168.
13. NGAL/MMP-9 as a Biomarker for Epithelial Ovarian Cancer: A Case-Control Diagnostic Accuracy Study. Saudi J Med Med Sci. 2022 Jan-Apr;10(1):25-30. DOI: 10.4103/sjmms. sjmms_581_21. Epub 2022 12th January. PMID: 35283706; PMCID: PMC8869267.
14. Analysis of Prediagnostic Circulating Levels of Gonadotropins and Androgens with Risk of Epithelial Ovarian Cancer. J Lab Physicians. 2022 Jan. DOI: 10.1055/s-0041-1741443.
15. A New Hope in Type 2 Diabetes Mellitus Management: Sodium-Glucose Cotransporter 2 Inhibitors. Cureus. 2021 Sep 26;13(9):e18300. DOI: 10.7759/cureus. 18300. PMID: 34722075; PMCID: PMC8548046.
16. A Molecular Insight of the Role of PIN-1 Promoter Polymorphism (− 667C > T; rs2233679) in Chronic Kidney Disease Patients with Secondary Hyperparathyroidism. Indian Journal of Clinical Biochemistry. 2021. Aug. DOI: 10.1007/s12291-021-00997-8.
17. Analysis of the Prevalence and Severity of Dysregulated Bone Mineral Homeostasis in Nondialyzed Chronic Kidney Disease Patients. J Lab Physicians. 2021. Jul. DOI: 10.1055/s-0041-1732495.
18. Epigenetic Silencing of DAPK1and p16INK4a Genes by CpG Island Hypermethylation in Epithelial Ovarian Cancer Patients. Indian J Clin Biochem. 2021 Apr;36(2):200-207. doi: 10.1007/s12291-020-00888-4. Epub 2020 May 16. PMID: 33867711; PMCID: PMC7994475.
19. Hyperinsulinemia and Hypoadiponectinemia are Associated with Increased Risk for Occurrence of Ovarian Cancer in Non-diabetic Women of North Indian Population. Indian J Clin Biochem. 2021 Apr;36(2):221-227. doi: 10.1007/s12291-020-00891-9. Epub 2020 May 13. PMID: 33867714; PMCID: PMC7994492.
20. Potential impact of (rs 4645878) BAX promoter -248G>A and (rs 1042522) TP5372Arg>pro polymorphisms on epithelial ovarian cancer patients. Clin Transl Oncol.2015 Jul 25. [Epub ahead of print] PubMed PMID: 26209050
21. TP53 Gene Polymorphism in Epithelial Ovarian Carcinoma Patients from North Indian Population and its Pro/Pro Variant is Potentially Contributing to Cancer Susceptibility. J Genet Syndr Gene Ther. 2013;4(5):145.
22. Association of Anti-TPO Antibodies with Insulin Resistance in Patients of Hypothyroidism with Metabolic Syndrome: A Cross-sectional Study. J Clin of Diagn Res.2020;14(10):BC09-BC13. https://www.doi.org/10.7860/JCDR/2020/45695/14123
23. Association of High Levels of High-Sensitive C-Reactive Protein with Metabolic Syndrome- A Cross-sectional Study. National Journal of Laboratory Medicine. 2021 Jan, Vol-10(1): BO01-BO05.
24. Evaluation of serum vitamin B12 level in patients of metabolic syndrome. Int J Clin Biochem Res 2019;6(4):474-478.
25. Utility of serum HE4 level to diagnose epithelial ovarian cancer - A cross sectional study. MedPulse  International Journal of Biochemistry. September 2018; 7(3): 69-72
26. MDM2 promoter polymorphism (rs2279744) andserum estrogen level are associated with increased risk of epithelial ovarian cancer: A case-control study. International Journal of Clinical Biochemistry and Research. 2018;5:526-32.
27. Study to evaluate serum sodium, potassium and chloride level in malaria and its association with severity of malaria. International Journal of Clinical Biochemistry and Research. 2018;5:565-69.
28. Association of serum calcium level with metabolic syndrome: A case-control study. MedPulse International Journal of Biochemistry. September 2018; 7(3): 60-63.
29. Effect Of Hypothyroidism And Its Treatment On Proatherogenic Lipid Levels. International Journal Of Scientific Research, Volume-6 | Issue-9 | September-2017 | ISSN No 2277 - 8179 | IF : 4.176 | IC Value : 78.46
30. Serum level of CA-125, Salivary Amylase and CEA in Epithelial Ovarian Cancer in North Indian Population. Sch. Acad. J. Biosci.2014; 2(9): 633-639.
31. RASSF1 and PTEN Promoter Hypermethylation Influences the Outcome in Epithelial Ovarian Cancer.  Clinical Ovarian and Other Gynecologic Cancer.2014;7:33–39.
32. Promoter Methylation of MGMT Gene in Ovarian Cancer. Int. J. Gen. Can. 2015; 2(1&2)
33. Job Related Stress is The Source of Stress among Male Partner of Infertile Couples. Journal of Psychology and Psychotherapy Research, 2015, 2, 42-49.
34. Plasma cell leukemia of IgG secreting type: A rare case. International Journal of Case Reports and Images. 2013;4(12):748–749

Publications (Book Chapters):-

1. IL-1 gene polymorphisms in solid tumors, accepted for publication by Elsevier publishers (In Press)
2. Dholariya SJ, Orrick JA. Biochemistry, Fructose Metabolism. 2022 Oct 17. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 35015453.
3. Sonagra AD, Dholariya SJ. Electrophoresis. 2022 Aug 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 36251838.

Awards and Honours:-

1. 1st Prize in Association of Medical Biochemists of India Conference (AMBICON) National P.G. Quiz, November, 2013.
2. 1st Prize Association of Medical Biochemists of India Conference (Delhi Chapter)-scientific meeting quiz, March 2014.
3. The utility of neutrophil gelatinase-associated lipocalin/matrix metallopeptidase-9 complex as a novel biomarker to diagnose epithelial ovarian cancer’ was adjudged for the “Award by the Organizing Committee-Oral Presentation Category during Association of Clinical Biochemists of India Conference (ACBICON) 2021 held virtually on 12th-15th December 2021.

Areas of Interest:-

Clinical chemistry, Endocrinology, Oncology and molecular biology 

Membership of Professional/Academic/ Research bodies

1. Life Member of Association of Clinical Biochemists of India (A.C.B.I.)
2.  Life Member of Association of Medical Biochemists of India (A.M.B.I.)
3. Life member of Society of Cancer Research Young Scientists Society
4. Life member of National Medicos Organization (N.M.O.)