Dr Ragini Singh


Dr. Ragini Singh

M.Sc. Ph.D.(Medicine) Biochemistry

    Publications (Research papers):-

    1.    Singh RD. Preface: Oral Cancer: New Insights in Diagnosis, Prognosis, Therapeutics to Management and Reconstruction. Crit Rev Oncog. 2022;27(4):xi-xii. doi: 10.1615/CritRevOncog.v27.i4.40. PMID: 37199298.
    2.    Singh RD, Patel KA, Patel JB, Patel PS. Association of Interactions between Metabolic 'Caretaker' Genes, p53, MDM2, and Tobacco Use with the Risk of Oral Cancer: A Multifactor Dimensionality Reduction Approach. Asian Pac J Cancer Prev. 2023 Apr 1;24(4):1231-1237. doi: 10.31557/APJCP.2023.24.4.1231. PMID: 37116145. [IF:1.89]
    3.    Dholariya S, Singh RD, Sonagra A, Yadav D, Vajaria BN, Parchwani D. Integrating Cutting-Edge Methods to Oral Cancer Screening, Analysis, and Prognosis. Critical Reviews™ in Oncogenesis. 2023;28(2):11-44. doi:10.1615/CritRevOncog.2023047772. [IF:1.04] (Corresponding Author)
    4.    Singh RD, Avadhesh A, Sharma G, Dholariya S, Shah RB, Goyal B, Gupta SC. Potential of cytochrome P450, a family of xenobiotic metabolizing enzymes, in cancer therapy. Antioxid Redox Signal. 2022 Oct 14. doi: 10.1089/ars.2022.0116. Epub ahead of print. PMID: 36242099. [IF:7.46]
    5.    Dholariya S, Parchwani D, Dutta S, Singh R. Clinical efficacy and safety of dasiglucagon in severe hypoglycemia associated with patients of type 1 diabetes mellitus: a systematic review and meta-analysis. Expert Rev Clin Pharmacol. 2023 Jan;16(1):61-71. doi: 10.1080/17512433.2023.2138343. Epub 2022 Oct 25. PMID: 36266088. [IF: 4.1] (Corresponding Author)
    6.    Patel N, Padhiyar J, Singh R, Bloch A, Babaria S. Comparative evaluation of host immune response and cytokine signature pertaining to Th1 and Th2 immune arms in serum and tissue among patients of acute localised vs. chronic disseminated dermatophytosis. Mycoses. 2022 Sep;65(9):877-886. doi: 10.1111/myc.13479. Epub 2022 Jul 8. PMID: 35673954. [IF:4.93].
    7.    Singh RD, Patel KA, Patel JB, Patel PS. Alterations in p53 Influence hTERT, VEGF and MMPs Expression in Oral Cancer Patients. Asian Pac J Cancer Prev. 2022 Sep 1;23(9):3141-3149. doi: 10.31557/APJCP.2022.23.9.3141. PMID: 36172677; PMCID: PMC9810300. [IF:1.89]
    8.    Parchwani D, Sonagra AD, Dholariya S, Motiani A, Singh R. COVID-19-related liver injury: Focus on genetic and drug-induced perspectives. World J Virol. 2023 Jan 25;12(1):53-67. doi: 10.5501/wjv.v12.i1.53. PMID: 36743658; PMCID: PMC9896591.
    9.    Dholariya S, Parchwani D, Radadiya M, Singh RD, Sonagra A, Patel D, Sharma G. CRISPR/Cas9: A Molecular Tool for Ovarian Cancer Management beyond Gene Editing. Crit Rev Oncog. 2022;27(4):1-22. doi: 10.1615/CritRevOncog.2022043814. PMID: 37199299. [IF:1.04] (Corresponding Author)
    10.    Parchwani D, Dholariya S, Katoch C, Singh R. Growth differentiation factor 15 as an emerging novel biomarker in SARS-CoV-2 infection. World J Methodol. 2022 Sep 20;12(5):438-447. doi: 10.5662/wjm.v12.i5.438. PMID: 36186744; PMCID: PMC9516548.
    11.    Parchwani D, Dholariya S, Patel DD, Agravatt A, Uperia J, Parchwani T, Singh R, Radadiya M, Desai Y. Association of the Human Leptin Receptor Gene (rs1137101; Gln223Arg) Polymorphism and Circulating Leptin in Patients with Metabolic Syndrome in the Indian Population. Ind J Clin Biochem (2022). [DOI: 10.1007/s12291-022-01065-5]. [IF:1.38]
    12.    Dholariya S, Singh RD, Radadiya M, Parchwani D, Sharma G, Mir R. Role of the Tumor Microenvironment and the Influence of Epigenetics on the Tumor Microenvironment in Oral Carcinogenesis: Potential Implications. Crit Rev Oncog. 2022;27(4):47-64. doi: 10.1615/CritRevOncog.2022047088. PMID: 37199302. [IF:1.04] (Corresponding Author)
    13.    Dholariya S, Parchwani DN, Singh R, Radadiya M, Katoch CDS. Utility of P-SEP, sTREM-1 and suPAR as Novel Sepsis Biomarkers in SARS-CoV-2 Infection. Indian J Clin Biochem. 2022 Apr;37(2):131-138. doi: 10.1007/s12291-021-01008-6. Epub 2021 Oct 6. PMID: 34642555; PMCID: PMC8494168.
    14.    Singh D, Patel KC, Singh RD. Achieving coronal plane alignment in total knee arthroplasty through modified preoperative planning based on long-leg radiographs: a prospective study. J Exp Orthop. 2021 Nov 2;8(1):100. doi: 10.1186/s40634-021-00418-y. PMID: 34729656; PMCID: PMC8563908.
    15.    Dholariya S, Parchwani DN, Singh R, Sonagra A, Motiani A, Patel D. Notable and Emerging Variants of SARS-CoV-2 Virus: A Quick Glance. Indian J Clin Biochem. 2021 Oct;36(4):451-458. doi: 10.1007/s12291-021-00991-0. Epub 2021 Jun 28. PMID: 34219999; PMCID: PMC8237041.
    16.    Parchwani D, Dholariya SJ, Takodara S, Singh R, Sharma VK, Saxena A, Patel DD, Radadiya M. Analysis of Prediagnostic Circulating Levels of Gonadotropins and Androgens with Risk of Epithelial Ovarian Cancer. J Lab Physicians. 2022 Jan 18;14(1):47-56. doi: 10.1055/s-0041-1741443. PMID: 36105913; PMCID: PMC9465621.DOI: 10.1055/s-0041-1741443
    17.    Patel DD, Parchwani D, Vachhani U, Parchwani T, Raghavani P, Rajput A, Dholariya S, Singh R. A Molecular Insight of the Role of PIN-1 Promoter Polymorphism (- 667C > T; rs2233679) in Chronic Kidney Disease Patients with Secondary Hyperparathyroidism. Indian J Clin Biochem. 2022 Jul;37(3):319-327. doi: 10.1007/s12291-021-00997-8. Epub 2021 Aug 3. PMID: 35873609; PMCID: PMC9300778. 
    18.    Singh RD, Patel KA, Patel JB, Pandya SJ, Patel PS. Evidence of Association of CYP1A1 Expression in Blood Lymphocytes and Clinicopathological Variables in Oral Cancer. Indian J Clin Biochem. 2022 Apr;37(2):178-184. doi: 10.1007/s12291-021-00958-1. Epub 2021 Feb 12. PMID: 35463108; PMCID: PMC8993998.
    19.    Patel NH, Padhiyar JK, Singh R, Patel T. Total serum IgE level in patients of dermatophytosis and its association with various clinical parameters. Indian J Dermatol Venereol Leprol. 2021 Mar-Apr;87(2):290-292. doi: 10.25259/IJDVL_1043_19. PMID: 33769756.
    20.    Patel KR, Vajaria BN, Singh RD, Begum R, Patel PS. Clinical implications of p53 alterations in oral cancer progression: a review from India. Exp Oncol. 2018 Mar;40(1):10-18. PMID: 29600984. 
    21.    Singh RD, Patel KR, Patel PS. "p53 mutation spectrum and its role in prognosis of oral cancer patients: A study from Gujarat, West India". Mutat Res. 2016 Jan;783:15-26. doi: 10.1016/j.mrfmmm.2015.12.001. Epub 2015 Dec 3. PMID: 26687995.
    22.    Singh RD, Haridas N, Shah FD, Patel JB, Shukla SN, Patel PS. Gene polymorphisms, tobacco exposure and oral cancer susceptibility: a study from Gujarat, West India. Oral Dis. 2014 Jan;20(1):84-93. doi: 10.1111/odi.12079. Epub 2013 Feb 28. PMID: 23444898. (The paper selected as landmark paper in Indian Cancer Congress, New Delhi, 2013)
    23.    Singh RD, Nilayangode H, Patel JB, Shah FD, Shukla SN, Shah PM, Patel PS. Combined evaluation of matrix metalloproteinases and their inhibitors has better clinical utility in oral cancer. Int J Biol Markers. 2011 Jan-Mar;26(1):27-36. doi: 10.5301/jbm.2011.6359. PMID: 21337314.
    24.    Singh RD, Haridas N, Patel JB, Shah FD, Shukla SN, Shah PM, Patel PS. Matrix metalloproteinases and their inhibitors: correlation with invasion and metastasis in oral cancer. Indian J Clin Biochem. 2010 Jul;25(3):250-9. doi: 10.1007/s12291-010-0060-8. Epub 2010 Aug 25. PMID: 21731196; PMCID: PMC3001841. (The paper was awarded as best paper in the journal during -2010)

    Publication (Book chapters):-

    1.    Sonagra, A. D., Singh, R., Dholariya, S., Motiani , A., & Parchwani, D. (2022). Preeclampsia and Oxidative Stress: A Review. Current Innovations in Medicine and Medical Science Vol. 5, 102–109. https://doi.org/10.9734/bpi/cimms/v5/16536D  2.    Singh R. IL-1 gene polymorphisms in solid tumors, Accepted for publication by Elsevier publishers (In press)


    Awards and Honours:-

    KPS-PS Sinha Award for best paper published: The paper “Matrix Metalloproteinases and Their Inhibitors: Correlation with Invasion and Metastasis in Oral Cancer” published in Indian Journal of Clinical Biochemistry was adjudged as the best paper published in the journal.

    Areas of Interest:-

    Onco-genetics, Onco-immunology, Molecular biology of oral cancer-micrometastases, circulating tumor cells, and circulating nucleic acids (ctDNA, microRNAs).


    Membership of Professional/Academic/ Research bodies

    Association of Clinical Biochemists and Microbiologists- Life member


    ORCID/Pubmed/Research gate link 

    ORCID: 0000-0003-2397-9023/ https://www.ncbi.nlm.nih.gov/myncbi/ragini.singh.1/bibliography/public/